Commercialization


  • bottle of Rezdiffra
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    Courtesy of Madrigal
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    As Madrigal faces MASH rivals, keeping patients is as critical as finding new ones

    Madrigal’s drug Rezdiffra has exceeded expectations, and the company plans to stay ahead of incoming competition with a highly targeted patient approach.

    By Kelly Bilodeau • Nov. 19, 2025
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    Is that pharma influencer human or AI?

    Agentic AI is making its way into pharma marketing — and raising a slew of potential challenges around regulations and ethics.

    By Nov. 14, 2025
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    Permission granted by Sarepta Therapeutics
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    Drugs are winning approval even when trials fail — but should they?

    About 10% of FDA-approved drugs in recent years have won clearance despite a trial failure, raising safety and ethical concerns.

    By Kelly Bilodeau • Nov. 12, 2025
  • Harout Semerjian, CEO, Geron
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    Permission granted by Geron
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    Q&A // First 90 Days

    After a lackluster first drug launch, a new CEO is finding Geron’s commercial footing

    Harout Semerjian, whose pedigree includes launching the Novartis cancer blockbuster Gleevec, is aiming to boost awareness about Geron’s Rytelo to give it momentum.

    By Alexandra Pecci • Nov. 12, 2025
  • Vials of Eisai and Biogen's new Alzheimer's drug Leqembi
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    Courtesy of Eisai
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    Alzheimer’s drug uptake hits its stride after a sluggish start

    Sales of Eli Lilly’s Kisunla, and Eisai and Biogen’s Leqembi are on the rise as doctors grow more confident and new dosing options ease treatment hurdles.

    By Kelly Bilodeau • Nov. 10, 2025
  • Keytruda Qlex
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    Courtesy of Merck
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    Half of Merck’s sales are in jeopardy. Can Keytruda’s sequel save the day?

    This week’s launch of subcutaneously administered Keytruda Qlex gives Merck a safety net for the cancer drug’s daunting patent cliff.

    By Oct. 2, 2025
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    Is pharma’s IRA pricing battle running out of steam?

    Despite recent court losses, the legal tides could still turn in the industry’s favor.

    By Sept. 26, 2025
  • colorful silhouette of a person, abstract concept with injection pen, blood glucose kit, scientific elements and insulin syringe
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    A brewing GLP-1 showdown, from Big Pharma pills to a biotech implant

    Newcomers looking for a way into the obesity space are developing unique methods to snag market share.

    By Amy Baxter • Aug. 27, 2025
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    The biggest Big Pharma losers in the first half of 2025

    What goes up must come down — here are the major drugs falling the hardest at the top companies so far this year.

    By Aug. 21, 2025
  • Robert F. Kennedy Jr. in a blue stripe suit points while speaking
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    Andrew Harnik via Getty Images
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    MAHA leaders may take aim at pharma DTC advertising

    RFK Jr. has his sights set on increasing advertising enforcement against pharmas, but may not come down as hard on the industry as previously thought.

    By Amy Baxter • Aug. 20, 2025
  • Boxes of the diabetes drug Ozempic rest on a pharmacy counter on April 17, 2023 in Los Angeles, California.
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    Mario Tama / Getty via Getty Images
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    Despite FDA ruling, compounded GLP-1s are still giving Novo and Lilly headaches on the market

    Copycat weight loss drugs were supposed to be pulled from the market, but pharmacies have found a loophole. 

    By Amy Baxter • Aug. 18, 2025
  • Eli Lilly
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    Scott Olson via Getty Images
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    3 ways the GLP-1 market has changed shape this year

    Novo Nordisk and Eli Lilly’s quarterly earnings revealed shifting dynamics in the lucrative obesity space.

    By Amy Baxter • Aug. 12, 2025
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    As gene therapies falter on the market, this biopharma is aiming to defy the odds

    After a strong launch for its cancer gene therapy, Ferring Pharmaceuticals is setting the stage for long-term growth.

    By Aug. 8, 2025
  • A sign with the Roche logo stands in front of a tall building.
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    Permission granted by Roche
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    Roche pushes ahead with late-comer strategy in obesity

    The Swiss pharma company announced several updates to its obesity portfolio in its latest earnings report.

    By Amy Baxter • July 30, 2025
  • A sign spelling Novartis hangs on the side of a building.
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    Novartis’ Zolgensma sales fall again as gene therapy market woes persist

    Novartis has seen sales decline in a difficult gene therapy market. Is there hope on the horizon?

    By July 22, 2025
  • Large letters spelling Amgen are seen by a wall
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    Mario Tama via Getty Images
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    3 major patent losses this year — and a key strategy to fill the gaps

    Despite promising pipelines, most new launches are missing sales targets, forcing pharmas to rethink sales strategies.

    By Kelly Bilodeau • July 21, 2025
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    Q&A

    Need a DTC platform? Here’s how one company built its own.

    Currax Pharmaceuticals was ahead of the curve when it set up a direct access platform for its obesity med. 

    By Amy Baxter • July 14, 2025
  • A low stone wall partially obscured by long grass bears a Merck & Co. logo
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    Jason Doiy via Getty Images
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    With Verona deal, Merck wagers on strength of lung drug’s patents

    The main patent for Ohtuvayre, the COPD drug at the heart of Verona’s $10 billion sale, expired in 2020. For Merck to make good on the deal, other secondary patents will need to hold up.

    By Jonathan Gardner • July 11, 2025
  • President Donald Trump speaks during a cabinet meeting at the White House on July 8, 2025, in Washington, D.C.
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    Andrew Harnik via Getty Images
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    Trump says ‘very high’ pharmaceutical tariffs coming soon

    While Trump indicated drug levies would be as high as 200%, he added that pharma firms would first be given time to bring manufacturing back to the U.S.

    By Philip Neuffer • July 9, 2025
  • Close-Up of Semaglutide Injection Pen Needle for Weight Loss Treatment
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    Getty Images
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    GLP-1 roadblocks: Discontinuation rates soar as insurers clamp down

    As more drugmakers aim for the lucrative weight loss market, patient challenges linger.

    By Amy Baxter • July 7, 2025
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    Justin Sullivan via Getty Images
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    3 of the year’s most notable FDA nods

    The agency has granted approvals steadily in the first part of the year, including nods for several breakthrough therapies.

    By June 27, 2025
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    Biogen scores Cannes Festival win with dark humored campaign

    The company’s unique campaign for a rare, terminal illness nabbed millions of views and a spot on the main stage at the Cannes Lions Festival of Creativity.

    By Alexandra Pecci • June 24, 2025
  • pills lie instead of eyes on a one hundred dollar bill in close-up.
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    Megablockbusters are the holy grail. Here’s how drugmakers are getting there.

    More drugs surpassed $10 billion in revenue last year than ever before.

    By Amy Baxter • June 23, 2025
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    Is DTC pharma advertising coming to an end?

    A bill introduced in Congress fulfills a Trump administration goal of ending direct pharma ads to patients.

    By Amy Baxter • June 18, 2025
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    Chip Somodevilla via Getty Images
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    The MAHA agenda won’t include expanding GLP-1 coverage — for now

    Despite axing a Biden-era proposal for government coverage of obesity drugs, health officials have signaled a potential path forward.

    By Amy Baxter • June 2, 2025